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The Early Rat

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The Early Rat

Post by Karen on Sun 28 Feb 2010 - 11:50

ART AND ARTISTS.

THE EARLY RAT.

Whistler's Nocturne in Blue and Gold, Valparaiso, was in the collection of Mr. Hill in Brighton, and one day the master paid a visit to the galleries. "I was shown into the galleries," he said, and, of course, took a chair and sat looking at my beautiful Nocturne; then, as there was nothing else to do, I went to sleep." The owner of the collection came in a little later and found him still sleeping. Whistler did not encourage his pupils to praise the works of others. Once Walter Sickert wrote an article in which he lauded Lord Leighton's "Harvest Moon," and received a telegram from Whistler. Chelsea, to Sickert, Hampstead: "The Harvest Moon" rises over Hampstead and the cocks of Chelsea crow." Another pupil received a much more bitter rebuke when, foreseeing that Whistler's presidency of the Royal Society of British Artists was nearing its end, he handed in his resignation. "The early rat," was Whistler's smiling comment. In the "Gentle Art of Making Enemies" he disposes of this pupil without naming him, but with this final hint, "You will blow out your brains, of course."

Source: Otago Witness, Issue 2834, 8 July 1908, Page 86
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Re: The Early Rat

Post by Guest on Mon 28 Jun 2010 - 4:51

Rat pups were treated from birth to
5 days of age with the vitamin K antagonist warfarin in order to
investigate possible
functions of the vitamin K-dependent dentin Gla protein (DGP)
in tooth development. Warfarin completely eliminated the
immunocytochemically
detectable DGP which is a prominent feature of dentin in
control rat pups, and also caused an increased concentration of DGP
in odontoblasts. Warfarin treatment did not affect the
ultrastructure of cells or the extracellular matrix in the tooth germs.
The width of the predentin layer, which is considered to be
correlated with the rate of mineralization, was unchanged. These
results are the first to demonstrate that warfarin treatment
prevents the accumulation of DGP in dentin, and that the deposition
of DGP has no influence on the overall rate of dentin matrix
mineralization in tooth germs.

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